cytokine production in hymenolepis nana infection

نویسندگان

aboulghasem ajami

department of immunology, sari medical school, mazandaran university of medical sciences, sari, iran alireza rafiei

department of immunology, sari medical school, mazandaran university of medical sciences, sari, iran

چکیده

background: although many experimental studies provide convincing evidence that type ii immunity is protective against helminths, recent data in mice demonstrate that th1 is also impor-tant in some cestodes like hymenolepis nana. objective: to identify the role of th1 and th2 lymphocytes in immunity against h. nana, the levels of il-12, ifnγ, il-5, and il-13 were de-termined in serum of humans infected with this cestode. methods: a total of 31 patients (case) with h. nana infection and 30 clinically healthy individuals (control) was included in this study. measurements of il-12, ifnγ, il-13 and il-5 in serum samples were performed by solid-phase sandwich enzyme linked immunosorbant assay. differential leukocyte count was also done. t test, mann whitney u test and wilcoxan w test were used for data analysis. results: the mean concentrations of ifnγ, il-12 and il-5 in the sera of patients with h. nana infection were higher than the control group, but only the differences between the concentrations of ifnγ (p

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Cytokine Production in Hymenolepis Nana Infection

Background: Although many experimental studies provide convincing evidence that type II immunity is protective against helminths, recent data in mice demonstrate that Th1 is also impor-tant in some cestodes like Hymenolepis nana. Objective: To identify the role of Th1 and Th2 lymphocytes in immunity against H. nana, the levels of IL-12, IFNγ, IL-5, and IL-13 were de-termined in serum of humans ...

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Cytokine production in Hymenolepis nana infection.

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عنوان ژورنال:
iranian journal of immunology

جلد ۴، شماره ۴، صفحات ۲۳۶-۲۴۰

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