cytokine production in hymenolepis nana infection
نویسندگان
چکیده
background: although many experimental studies provide convincing evidence that type ii immunity is protective against helminths, recent data in mice demonstrate that th1 is also impor-tant in some cestodes like hymenolepis nana. objective: to identify the role of th1 and th2 lymphocytes in immunity against h. nana, the levels of il-12, ifnγ, il-5, and il-13 were de-termined in serum of humans infected with this cestode. methods: a total of 31 patients (case) with h. nana infection and 30 clinically healthy individuals (control) was included in this study. measurements of il-12, ifnγ, il-13 and il-5 in serum samples were performed by solid-phase sandwich enzyme linked immunosorbant assay. differential leukocyte count was also done. t test, mann whitney u test and wilcoxan w test were used for data analysis. results: the mean concentrations of ifnγ, il-12 and il-5 in the sera of patients with h. nana infection were higher than the control group, but only the differences between the concentrations of ifnγ (p
منابع مشابه
Cytokine Production in Hymenolepis Nana Infection
Background: Although many experimental studies provide convincing evidence that type II immunity is protective against helminths, recent data in mice demonstrate that Th1 is also impor-tant in some cestodes like Hymenolepis nana. Objective: To identify the role of Th1 and Th2 lymphocytes in immunity against H. nana, the levels of IL-12, IFNγ, IL-5, and IL-13 were de-termined in serum of humans ...
متن کاملCytokine production in Hymenolepis nana infection.
BACKGROUND Although many experimental studies provide convincing evidence that type II immunity is protective against helminths, recent data in mice demonstrate that Th1 is also important in some cestodes like Hymenolepis nana. OBJECTIVES To identify the role of Th1 and Th2 lymphocytes in immunity against H. nana, the levels of IL-12, IFNgamma, IL-5, and IL-13 were determined in serum of huma...
متن کاملHymenolepis nana
RATIONALE There is evidence that parasitic helminths can ameliorate colitis in animal models and humans. Although infections with Hymenolepis sp. are clinically benign, the immunomodulatory interactions between host and parasite are largely unknown. PATIENT CONCERNS In this study we examined the intestinal mucosa of an adult asymptomatic patient harboring adult and larval dwarf tapeworms (Hym...
متن کاملHymenolepis Nana
Sill,?Captain Stewart begins his note on Hymenolepis nana, in the June number of the Indian Medical Gazette, with the words, " Ah far as the literature at the disposal of the present writer permits of a statement, Hymenole/iis nana has been recorded on one occasion only from India, nnmely, by Capt:iin M. Foster lleaney from the Ward a district. (6)." Number (6) in Captain Stewart's references r...
متن کاملSkin eruption associated with Hymenolepis nana infection.
International Journal of Dermatology 2004, 43 , 357–359 357 A 56-year-old man presented with a recurrent cutaneous eruption of the trunk, associated with itching, which had lasted for several months. Antihistamines, such as cetirizine, loratadine, and fexofenadine, and topical steroids had been used with only temporary relief. Recently, the cutaneous manifestations had become continuous and ver...
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عنوان ژورنال:
iranian journal of immunologyجلد ۴، شماره ۴، صفحات ۲۳۶-۲۴۰
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